Publications

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NCBI Bibliography

Lab members in bold.

In press

Kissel LT & Werling DM. Neural transcriptomic analysis of sex differences in autism spectrum disorder: Current insights and future directions. Biological Psychiatry. doi: 10.1016/j.biopsych.2020.11.023. PMID: 33551190. Review. Link

2020

Werling DM*, Pochareddy S*, Choi J*, An J-A*, Sheppard B, Peng M, Li Z, Dastmalchi C, Santpere G, Sousa AMM, Tebbenkamp ATN, Kaur N, Gulden FO, Breen MS, Liang L, Gilson MC, Zhao X, Dong S, Klei L, Cicek AE, Buxbaum JD, Adle-Biassette H, Thomas J-L, Aldinger KA, O’Day DR, Glass IA, Zaitlen NA, Talkowski ME, Roeder K, State MW, Devlin B, Sanders SJ, and Sestan N. Whole-genome and RNA sequencing reveal variation and transcriptomic coordination in the developing human prefrontal cortex. Cell Reports, 31, 107489, 2020. doi: 10.1016/j.celrep.2020.03.053 *These authors contributed equally to this work. Link

2019

Werling DM. Clinically defined subtypes of bipolar disorder are reflected in genomic architecture. Biological Psychiatry, 86(2), 78-80, 2019. doi: 10.1016/j.biopsych.2019.05.010. PMID: 31272529. Commentary. Link

2018

An J-A*, Lin K*, Zhu L*, Werling DM*, Dong S, Brand H, Wang HZ3, Zhao X, Schwartz GB, Collins RL, Currall BB, Dastmalchi C, Dea J, Duhn C, Gilson MC, Klei L, Liang L, Markenscoff-Papadimitriou E, Pochareddy S, Ahituv N, Buxbaum JD, Coon H, Daly MJ, Kim YS, Marth GT, Neale BM, Quinlan AR, Rubenstein JL, Sestan N, State MW, Willsey AJ, Talkowski ME, Devlin B, Roeder K, Sanders SJ. Genome-wide de novo risk score implicates promoter variation in autism spectrum disorder. Science, 362(6420), 2018. PMID: 30545852. *These authors contributed equally to this work. Link

Li M*, Santpere G*, Kawasawa YI*, Evgrafov OV*, Gulden FO*, Pochareddy S*, Sunkin SM*, Li Z*, Shin Y*, Kitchen RR, Zhu Y, Werling DM, Sousa AMM, Kang HJ, Pletikos M, Choi J, Muchnik S, Xu X, Wang D, Liu S, Giusti-Rodríguez P, de Leeuw CA, Pardiñas AF, BrainSpan Consortium, PsychENCODE Consortium: Developmental Subgroup, Hu M, Jin F, Li Y, Owen MJ, O’Donovan MC, Walters JTR, Posthuma D, Sullivan PF, Levitt P, Weinberger DR, Kleinman JE, Geschwind DH, Sanders SJ, Hawrylycz MJ, Gerstein MB, Lein ES, Knowles JA, Sestan N. Integrative functional genomic analysis of human brain development and neuropsychiatric risk. Science, 362(6420), 2018. PMID: 30545854. *These authors contributed equally to this work. Link

Werling DM*, Brand H*, An J-A*, Stone MR*, Zhu L*, Glessner JT, Collins RL, Dong S, Layer RM, Markenscoff-Papadimitriou E-C, Farrell A, Schwartz GB, Wang HZ, Currall BB, Zhao X, Dea J, Duhn C, Erdman C, Gilson M, Yadav R, Handsaker RE, Kashin S, Klei L, Mandell JD, Nowakowski TJ, Liu Y, Pochareddy S, Smith L, Walker MF, Waterman MJ, He X, Kriegstein AR, Rubenstein JL, Sestan N, McCarroll SA, Neale BM, Coon H, Willsey AJ, Buxbaum JD, Daly MJ, State MW, Quinlan A, Marth GT, Roeder K, Devlin B, Talkowski ME, Sanders SJ. An analytical framework for whole-genome sequence data and its implications for autism spectrum disorder. Nature Genetics, 50, 727-736, 2018. doi: 10.1038/s41588-018-0107-y. PMID: 29700473. *These authors contributed equally to this work. Link

2017

Sanders SJ, Neale BM, Huang H, Werling DM, An J-A, Dong S, Abecasis G, Arguello A, Blangero J, Boehnke M, Daly MJ, Eggan K, Geschwind DH, Glahn DC, Goldstein DB, Gur RE, Handsaker RE, McCarroll SA, Ophoff RA, Palotie A, Pato CN, Sabatti C, State MW, Willsey AJ, Hyman SE, Addington AM, Lehner T, Freimer NB. Whole genome sequencing in psychiatric disorders: the WGSPD consortium. Nature Neuroscience, 20, 1661-1668, 2017. doi:10.1038/s41593-017-0017-9. PMID: 29184211. Comment. Link

Grzadzinski R, Lord C, Sanders SJ, Werling D, Bal VH. Children with autism spectrum disorder who improve with fever: Insights from the Simons Simplex Collection. Autism Research, Epub ahead of print, 2017. doi: 10.1002/aur.1856. PMID: 28861935. Link

Bishop SL, Farmer C, Bal V, Robinson EB, Willsey AJ, Werling DM, Havdahl KA, Sanders SJ, & Thurm A. Identification of developmental and behavioral markers associated with genetic abnormalities in autism spectrum disorder. American Journal of Psychiatry, 174(6), 576-585, 2017. doi: 10.1176/appi.ajp.2017.16101115. PMID: 28253736. Link

2016

Werling DM. The role of sex-differential biology in risk for autism spectrum disorder. Biology of Sex Differences, 7(1), 58, 2016. doi: 10.1186/s13293-016-0112-8. PMID: 27891212. Review. Link

Werling DM, Parikshak NN, & Geschwind DH. Gene expression in human brain implicates sexually dimorphic pathways in autism spectrum disorders. Nature Communications, 7, 10717, 2016. doi: 10.1038/ncomms10717. PMID: 26892004. Link

Werling DM & Sanders SJ. Gene coexpression modules in human cognition. Nature Neuroscience, 19(2), 173-175, 2016. doi: 10.1038/nn.4226. PMID: 26814582. Commentary. Link

2015

Sanders SJ, He X, Willsey AJ, Ercan-Sencicek AG, Samocha KE, Cicek AE, Murtha MT, Hus Bal V, Bishop SL, Dong S, Goldberg AP, Jinlu C, Keaney JF 3rd, Klei L, Mandell JD, Moreno-De-Luca D, Poultney CS, Robinson EB, Smith L, Solli-Nowlan T, Su MY, Teran NA, Walker MF, Werling DM, Beaudet AL, Cantor RM, Fombonne E, Geschwind DH, Grice DE, Lord C, Lowe JK, Mane SM, Martin DM, Morrow EM, Talkowski ME, Sutcliffe JS, Walsh CA, Yu TW, Autism Sequencing Consortium, Ledbetter DH, Martin CL, Cook EH, Buxbaum JD, Daly MJ, Devlin B, Roeder K, & State MW. Insights into autism spectrum disorder genomic architecture and biology from 71 risk loci. Neuron, 87(6), 1215-1233, 2015. doi: 10.1016/j.neuron.2015.09.016. PMID: 26402605. Link

Werling DM & Geschwind DH. Recurrence rates provide evidence for sex-differential, familial genetic liability for autism spectrum disorders in multiplex families and twins. Molecular Autism, 6(27), 1-14, 2015. PMID: 25973164. Link

Lowe JK, Werling DM, Constantino JN, Cantor RM, & Geschwind DH. Social responsiveness, an autism endophenotype: Genomewide significant linkage to two regions on chromosome 8. American Journal of Psychiatry, 172(3), 266-275, 2015. doi: 10.1176/appi.ajp.2014.14050576. PMID: 25727539. Link

Oguro-Ando A, Rosensweig C, Herman E, Nishimura Y, Werling D, Bill BR, Berg JM, Gao F, Coppola G, Abrahams BS, & Geschwind DH. Increased CYFIP1 dosage alters cellular and dendritic morphology and dysregulates mTOR. Molecular Psychiatry, 20(9), 1069–1078, 2015. doi: 10.1038/mp.2014.124. PMID: 25311365. Link

2014

Werling DM, Lowe JK, Luo R, Cantor RM, & Geschwind DH. Replication of linkage for autism spectrum disorder at chromosome 20p13 and identification of suggestive sex-differential risk loci. Molecular Autism, 5(1), 13, 2014. PMID: 24533643. Link

2013

Werling DM & Geschwind DH. Understanding sex bias in autism spectrum disorder. Proceedings of the National Academy of Sciences, 110(13), 4868-4869, 2013. PMID: 23476067. Commentary. Link

Werling DM & Geschwind DH. Sex differences in autism spectrum disorders. Current Opinion in Neurology, 26(2), 146-153, 2013. PMID: 23406909. Review. Link

2010

Watson K, Werling DM, Zucker N, & Platt M. Altered social reward and attention in anorexia nervosa. Frontiers in Psychopathology, 1, 1-7, 2010. PMID: 21887145. Link